This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.
Immunogen Information
Immunogen
Synthetic peptide of human KRT14
Swissprot
P02533
Synonyms
CK 14CK-14ck14Cytokeratin 14Cytokeratin-14Cytokeratin14Dowling MearaEBS3EBS4Epidermolysis bullosa simplexK14K1C14Keratin 14 (epidermolysis bullosa simplexDowling-MearaKoebner)Keratin 14KeratinKeratin type I cytoskeletal 14Keratintype I
Calculated MW
52 kDa
Gene Accession
NP_000517
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4