The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
Immunogen Information
Immunogen
Recombinant protein of human KRT19
Swissprot
P08727
Synonyms
40 kDa keratin intermediate filamentCK 19CK-19CK19Cytokeratin 19Cytokeratin-19K19K1C19K1CSKeratin 19Keratin type I 40 kDKeratin type I 40kDKeratin type I cytoskeletal 19Keratintype I cytoskeletal 19Keratintype I40 kdKeratin-19KRT19MGC1
Calculated MW
44 kDa
Gene Accession
BC007628
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4