CK19 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90720A
Immunohistochemistry of paraffin-embedded Human lung cancer using Krt19 Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human colon using Krt19 Polyclonal Antibody at dilution of 1:300
Product Name
CK19 Polyclonal Antibody
Catalog Number
RD90720A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19,one of type I keratins,is specifically expressed in the periderm,the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity,KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes,peripheral blood,and bone marrow of breast cancer patients. This antibody,generated against full length KRT19 protein,also recognizes KRT17,another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.
Immunogen Information
Immunogen
Recombinant Rat Krt19 protein expressed by E.coli
Swissprot
Q63279
Synonyms
40 kDa keratin intermediate filamentCK 19CK-19CK19Cytokeratin 19Cytokeratin-19K19K1C19K1CSKeratin 19Keratin type I 40 kDKeratin type I 40kDKeratin type I cytoskeletal 19Keratintype I cytoskeletal 19Keratintype I40 kdKera
Applications
Reactivity
Human
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas