CKAP4 (cytoskeleton-associated protein 4), also known as p63, CLIMP-63 or ERGIC-63, is a 602 amino acid single-pass type II transmembrane protein that links the endoplasmic reticulum (ER) to the cytoskeleton. Considered a novel protein in maintaining ER morphology, CKAP4 anchors the ER to microtubles which is required for maintaining ER spatial distribution during interphase of the cell cycle. CKAP4 can be reversibly palmitoylated and phosphorylated and is a major substrate of the palmitoyl acyltransferase, ZDHHC2.
Immunogen Information
Immunogen
Synthetic peptide of human CKAP4
Swissprot
Q07065
Synonyms
63 kDa membrane proteinCKAP 4Ckap4CKAP4Cytoskeleton associated protein 4Cytoskeleton-associated protein 4ERGIC 63ERGIC63MGC99554p63Transmembrane protein 63kD endoplasmic reticulum Golgi intermediate compartmentType II transmembrane protein p63
Calculated MW
66 kDa
Gene Accession
NP_006816
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:25-1:100
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4