Claudin 8 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD76289A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using Claudin 8 Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using Claudin 8 Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using Claudin 8 Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using Claudin 8 Polyclonal Antibody at dilution 1:50
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Overview
Circle
Product Name
Claudin 8 Polyclonal Antibody
Catalog Number
RD76289A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Circle
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.
Immunogen Information
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Immunogen
Synthetic peptide of human CLDN8
Swissprot
P56748
Synonyms
Claudin 8Claudin-8CLD8Cldn8Epididymis secretory protein Li 79HEL S 79OTTHUMP00000101915
Gene Accession
NP_955360
Applications
Circle
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas
Circle

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