CLCN7 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD252548A
Immunohistochemistry of paraffin-embedded Human breast cancer tissue  using CLCN7 Polyclonal Antibody at dilution of 1:105(×200)
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using CLCN7 Polyclonal Antibody at dilution of 1:105(×200)
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Overview

Circle
Product Name
CLCN7 Polyclonal Antibody
Catalog Number
RD252548A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.

Immunogen Information

Circle
Immunogen
Fusion protein of human CLCN7
Swissprot
P51798
Synonyms
Chloride channel protein 7CLC 7ClC-7ClC7CLCN7CLCN7FLJ26686FLJ39644FLJ46423H(+)/Cl(-) exchange transporter 7OPTA2OPTB4
Gene Accession
BC012737

Applications

Circle
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:100, ELISA 1:5000-1:10000
Concentration
1.56 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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