This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human CNOT2
Gene ID
4848
Swissprot
Q9NZN8
Synonyms
CNOT2CDC36HSPC131NOT2NOT2H
Calculated MW
35kDa/59kDa/98kDa/102kDa/104kDa
Observed MW
102kDa
Applications
Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.