COMP Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD267707A
Western blot analysis of extracts of various cell lines using COMP Polyclonal Antibody at dilution of 1:1000.
Immunofluorescence analysis of U2OS cells using COMP Polyclonal Antibody
Product Name
COMP Polyclonal Antibody
Catalog Number
RD267707A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
Immunogen Information
Immunogen
Recombinant fusion protein of human COMP (NP_000086.2).
Gene ID
1311
Swissprot
P49747
Synonyms
COMPEDM1EPD1MEDPSACHTHBS5TSP5
Calculated MW
77 kDa/82 kDa
Observed MW
110 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IF 1:10-1:100
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas