This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Connexin 43
Swissprot
P17302,P23242,P08050
Synonyms
Connexin 43Connexin-43Cx 43Cx43CXA1DFNB38Gap junction 43 kDa heart proteinGap junction alpha-1 proteinGap junction protein alpha 1 43kDa (connexin 43)Gap junction protein alpha 1 43kDaGap junction protein alpha likeGJA 1Gja1GJALODDODDDODOD
Calculated MW
43 kDa
Observed MW
43 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000, IHC 1:300-1:800
Concentration
0.53 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4