COPS5 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75240A
Western Blot analysis of Mouse liver tissue using COPS5 Polyclonal Antibody at dilution of 1:1550
Immunohistochemistry of paraffin-embedded Human colon cancer using COPS5 Polyclonal Antibody at dilution of 1:120
Product Name
COPS5 Polyclonal Antibody
Catalog Number
RD75240A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors
Immunogen Information
Immunogen
Recombinant protein of human COPS5
Swissprot
Q92905
Synonyms
38 kDa Mov34 homologCOP9 (constitutive photomorphogenic) homolog subunit 5COP9 constitutive photomorphogenic homolog subunit 5COP9 signalosome complex subunit 5COP9 signalosome subunit 5Cop9 subunit 5COPS 5cops5CSN 5CSN5CSN5JAB 1Jun activation
Calculated MW
38 kDa
Gene Accession
BC001187
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:150-1:500
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.