COQ6 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD87855A
Western blot analysis of extracts of various cell lines using COQ6 Polyclonal Antibody at 1:3000 dilution.
Western blot analysis of extracts of various cell lines using COQ6 Polyclonal Antibody at 1:3000 dilution.
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Overview

Circle
Product Name
COQ6 Polyclonal Antibody
Catalog Number
RD87855A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human COQ6
Gene ID
51004
Swissprot
Q9Y2Z9
Synonyms
COQ6CGI-10CGI10COQ10D6coenzyme Q6
Calculated MW
11kDa
Observed MW
11kDa

Applications

Circle
Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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