Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIb, which is highly similar to bovine COX VIIb protein and is found in all tissues. This gene may have several pseudogenes on chromosomes 1, 2, 20 and 22.
Immunogen Information
Immunogen
Recombinant protein of human COX7B
Swissprot
P24311
Synonyms
COX7BCOX7BCytochrome c oxidase chain VIIbCytochrome c oxidase polypeptide VIIbCytochrome c oxidase subunit 7BCytochrome c oxidase subunit 7B mitochondrialCytochrome c oxidase subunit VIIbmitochondrial
Calculated MW
9 kDa
Gene Accession
BC018386
Applications
Reactivity
Human,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4