Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. AEG is a sperm surface protein involved in the fusion of egg and sperm. Although CRISP-1 (also designated AEG-like protein, ARP, cysteine-rich secretory protein-1 or AEG-related protein) is not the ortholog of rodent AEG, it resembles AEG in that it is an epididymal secretory glycoprotein that binds to the postacrosomal region of the sperm head. CRISP-1 coats the postacrosomal region of sperm heads as they pass through the epididymis. CRISP-1 is found in all regions of the epididymis, ductus deferens, seminal plasma and sperm. CRISP-3 is expressed in pancreas and prostate tissues and, along with CRISP-1, is expressed in saliva.
Immunogen Information
Immunogen
Recombinant protein of human CRISP3
Swissprot
P54108
Synonyms
Aeg 2Aeg2CRIS3CRISP 3CRISP-3Crisp3CRS 3CRS3Cysteine rich secretory protein 3Cysteine-rich secretory protein 3dJ442L6.3MGC126588OTTHUMP00000016590OTTHUMP00000039911SGP 28SGP28SGP28 proteinSpecific granule protein (28 kDa)Specific granule
Gene Accession
BC069580
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4