Collapsin response mediator protein 3 is an enzyme that in humans is encoded by the CRMP3 gene.It is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.And plays a role in axon guidance, neuronal growth cone collapse and cell migration.Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL3 or DPYSL5. Interacts with PLEXA1. Phosphorylated upon DNA damage, probably by ATM or ATR.
Immunogen Information
Immunogen
Synthetic peptide of human DPYSL4
Swissprot
O14531
Synonyms
Collapsin response mediator protein 3CRMP 3CRMP-3CRMP3Dihydropyrimidinase like 4Dihydropyrimidinase related protein 4Dihydropyrimidinase-related protein 4DPYL4DPYSL4DRP 4DRP-4DRP4ULIP 4ULIP-4ULIP4UNC33 like phosphoprotein 4UNC33-like phosp
Calculated MW
62 kDa
Gene Accession
NP_006417
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4