CRTAM Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75133A
Western Blot analysis of 293T cell using CRTAM Polyclonal Antibody at dilution of 1:250
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CRTAM Polyclonal Antibody at dilution of 1:60
Product Name
CRTAM Polyclonal Antibody
Catalog Number
RD75133A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.
Immunogen Information
Immunogen
Recombinant protein of human CRTAM
Swissprot
O95727
Synonyms
CD355Class I MHC restricted T cell associated moleculeClass-I MHC-restricted T-cell-associated moleculeCRTAMCRTAMCytotoxic and regulatory T cell moleculeCytotoxic and regulatory T-cell molecule
Calculated MW
45 kDa
Observed MW
Refer to Figures
Gene Accession
BC070266
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas