CSMD1 CUB and Sushi multiple domains 1 is aproteinthat in humans is encoded by theCSMD1gene. It is a potential tumoursuppressor, the deletion of whicHuman, Mouseay result in head and neckcarcinomasbehaving more aggressively. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas.
Immunogen Information
Immunogen
Synthetic peptide of human CSMD1
Swissprot
Q96PZ7
Synonyms
CUB and sushi domain-containing protein 1CUB and Sushi multiple domains 1PPP1R24protein phosphatase 1regulatory subunit 24UNQ5952/PRO19863
Gene Accession
NP_150094
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4