Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human CSNK2A1
Swissprot
P68400
Synonyms
Casein kinase 2 alpha 1 polypeptideCasein kinase II alpha 1Casein kinase II alpha 1 subunitCasein kinase II alpha subunitCasein kinase II subunit alphaCK II alphaCK IICK2 alphaCK2 catalytic subunit alphaCK2A1CKIICKIIalphaCSK21CSNK2A1
Calculated MW
45 kDa
Gene Accession
BC011668
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4