CST3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90653A
Western blot with CST3 Polyclonal antibody at dilution of 1:500.lane 1:Hep G2 whole cell lysate, lane 2:PC-3 whole cell lysate, lane 3:Caco-2 whole cell lysate, lane 4:Mouse Kidney,lane 5:Rat Kidney
Immunohistochemistry of paraffin-embedded Human liver cancer using CST3 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human kidney using CST3 Polyclonal Antibody at dilution of 1:500
Product Name
CST3 Polyclonal Antibody
Catalog Number
RD90653A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration,shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions,establishing its role in vascular disease. In addition,this protein has been shown to have an antimicrobial function,inhibiting the replication of herpes simplex virus.
Immunogen Information
Immunogen
Recombinant Human CST3 protein expressed by E.coli
Swissprot
P01034
Synonyms
AD8Amyloid angiopathy and cerebral hemorrhageARMD11CST3 proteinCystatin 3CystatinCEpididymis secretory protein Li 2bA218C14.4Gamma traceHCCAAHEL S 2Neuroendocrine basic polypeptidePost gamma globulin
Calculated MW
25 kDa
Observed MW
26 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000, IHC 1:250-1:500
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas