This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
Immunogen Information
Immunogen
Synthetic peptide of human CTBP1
Swissprot
Q13363
Synonyms
BARSbrefeldin A- ribosylated substrateC terminal binding protein 1C-terminal-binding protein 1CTBPCtBP1CTBP1MGC104684
Gene Accession
NP_001319
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-250, ELISA 1:2000-10000
Concentration
1.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4