CYB5R3 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD219777A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using CYB5R3 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CYB5R3 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue  using CYB5R3 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CYB5R3 Polyclonal Antibody at dilution of 1:50(×200)
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Overview

Circle
Product Name
CYB5R3 Polyclonal Antibody
Catalog Number
RD219777A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
CYB5R3,also named as DIA1 and B5R,belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. It plays an essential role in the mitochondrial metabolism by its contribution to cellular redox homeostasis. Overstimulation of CYB5R3 associated with lipid rafts can account for the overshot of plasma membrane-focalized superoxide anion production that triggers the entry of CGN in the irreversible phase of apoptosis.

Immunogen Information

Circle
Immunogen
Synthetic peptide of human CYB5R3
Swissprot
P00387
Synonyms
B5RCyb5r3Cytochrome b5 reductase 3Cytochrome b5 reductaseDIA1Diaphorase 1Diaphorase-1NADH cytochrome b5 reductase 3NADH-cytochrome b5 reductase 3 membrane-bound formNADH-cytochrome b5 reductase 3 soluble formNB5R3OTTHUMP00000028761OTTHUMP00000
Gene Accession
NP000389

Applications

Circle
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
1.2 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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