CYBB Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD79186A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CYBB Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human brain tissue using CYBB Polyclonal Antibody at dilution 1:50
Variation
Quantity
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Overview
Product Name
CYBB Polyclonal Antibody
Catalog Number
RD79186A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles.
Immunogen Information
Immunogen
Synthetic peptide of human CYBB
Swissprot
P04839
Synonyms
AMCBX2CGDCGD91-phoxCY24BCYBBCytochrome b 245beta polypeptideCytochrome b(558) beta chainCytochrome b(558) subunit betaCytochrome b-245 heavy chainCytochrome b558 subunit betaGP91 PHOXgp91-1gp91-phoxGP91PHOXHeme-binding membrane glycoprotein
Gene Accession
NP_000388
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas