CYBB Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70473A
Immunohistochemistry analysis of paraffin-embedded mouse spleen using CYBB Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded rat spleen using CYBB Polyclonal Antibody at dilution of 1:400.
Product Name
CYBB Polyclonal Antibody
Catalog Number
RD70473A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles.
Immunogen Information
Immunogen
Recombinant protein corresponding to Mouse NOX2
Swissprot
Q61093
Synonyms
AMCBX2CGDCGD91-phoxCY24BCYBBCytochrome b 245beta polypeptideCytochrome b(558) beta chainCytochrome b(558) subunit betaCytochrome b-245 heavy chainCytochrome b558 subunit betaGP91 PHOXgp91-1gp91-phoxGP91PHOXHeme-binding membrane glycoprotein
Applications
Reactivity
Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:200-1:1000
Concentration
270 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas