This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide.
Immunogen Information
Immunogen
Synthetic peptide of human CYP2B6
Swissprot
P20813
Synonyms
14 cineole 2 exo monooxygenase11B1CP2B6CPB 6CPB6CYP 2B6CYP IIB6CYP2BCYP2B6CYP2B7CYP2B7PCYPIIB6Cytochrome P450 2B6Cytochrome P450 family 2 subfamily BCytochrome P450 family 2 subfamily B polypeptide 6Cytochrome P450 IIB1Cytochrome P450 phe
Calculated MW
56 kDa
Gene Accession
NP_000758
Applications
Reactivity
Human
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000
Concentration
1.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4