The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human CYB5A
Swissprot
P00167
Synonyms
CYB 5CYB 5ACYB5CYB5Cyb5aCytochrome b 5Cytochrome b5 (microsomal)Cytochrome b5Cytochrome b5 type A (microsomal)Cytochrome b5 type AMCB 5MCB5Microsomal cytochrome b5Microsomal cytochrome b5 type AType 1 cyt b5
Calculated MW
15 kDa
Gene Accession
NP_683725
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4