The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human DBN1 (NP_004386.2).
Gene ID
1627
Swissprot
Q16643
Synonyms
DBN1D0S117Edrebrin
Applications
Reactivity
Human
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:100
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
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