DDC Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD253391A
Western blot analysis of Human left kidney tissue and Human fetal liver tissue lysates using DDC Polyclonal Antibody at dilution of 1:800
Product Name
DDC Polyclonal Antibody
Catalog Number
RD253391A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human DDC
Swissprot
P20711
Synonyms
AADCAromatic L Amino Acid DecarboxylaseAromatic-L-amino-acid decarboxylaseDDCDDC_HUMANDOPA decarboxylase (aromatic L-amino acid decarboxylase)DOPA decarboxylase
Calculated MW
54 kDa
Observed MW
Refer to figures
Gene Accession
NP000781
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, ELISA 1:5000-1:10000
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas