Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes.
Immunogen Information
Immunogen
Fusion protein of human DENND6A
Swissprot
Q8IWF6
Synonyms
F116AFam116aFamily with sequence similarity 116 member Afamily with sequence similarity 116member AFLJ34969hypothetical protein LOC201627Protein FAM116A