This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
Immunogen Information
Immunogen
Recombinant fusion protein of human Desmin
Gene ID
1674
Swissprot
P17661
Synonyms
DESCSM1CSM2LGMD2RdesminDesmin
Calculated MW
58kDa/59kDa/60kDa
Observed MW
65KDa
Applications
Reactivity
Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:200-1:500
Concentration
1mg/mL
Storage Buffer
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.