DHCR24 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78345A
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using DHCR24 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using DHCR24 Polyclonal Antibody at dilution 1:40
Product Name
DHCR24 Polyclonal Antibody
Catalog Number
RD78345A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Immunogen Information
Immunogen
Recombinant protein of human DHCR24
Swissprot
Q15392
Synonyms
24 dehydrocholesterol reductase24-dehydrocholesterol reductase3 beta hydroxysterol delta 24 reductase3-beta-hydroxysterol delta-24-reductaseDCEDelta(24)-sterol reductaseDesmosterol to cholesterol enzymeDHC24Dhcr24Diminuto dwarf1 homologDiminuto/
Gene Accession
BC004375
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas