This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Synthetic peptide of human DICER1
Swissprot
Q9UPY3
Synonyms
DCRDCR1Dicer 1 ribonuclease IIIDicer 1 ribonuclease type IIIDicerDICERDICER1Double-strand-specific ribonucleaseEndoribonuclease DicerHelicase MOIHelicase with RNase motifHERNAKIAA0928MNG1RMSE2
Gene Accession
NP_085124
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4