DKC1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD81141A
Immunohistochemistry of paraffin-embedded Human lung cancer using DKC1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of NIH-3T3 cells using DKC1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U-2 OS cells using DKC1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
DKC1 Polyclonal Antibody
Catalog Number
RD81141A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant fusion protein of human DKC1 (NP_001354.1).
Gene ID
1736
Swissprot
O60832
Synonyms
DKC1CBF5DKCDKCXNAP57NOLA4XAP101
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,IF
Conjugation
Unconjugated
Dilution
IHC 1:50-1:100 IF 1:50-1:100
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas