DKK2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD266361A
Western blot analysis of extracts of various cell lines using DKK2 Polyclonal Antibody at dilution of 1:1000.
Product Name
DKK2 Polyclonal Antibody
Catalog Number
RD266361A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).
Immunogen Information
Immunogen
A synthetic peptide of human DKK2 (NP_055236.1).
Gene ID
27123
Swissprot
Q9UBU2
Synonyms
DKK2DKK-2
Calculated MW
28 kDa
Observed MW
30 kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas