Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.
Immunogen Information
Immunogen
Recombinant protein of human DLX4
Swissprot
Q92988
Synonyms
Beta protein 1BP1Distal less homeo box 7Distal less homeo box 9distal-less homeobox 4DLX4DLX4DLX7DLX8DLX9Homeobox protein DLX-4Homeobox protein DLX-7Homeobox protein DLX-8Homeobox protein DLX4
Gene Accession
BC016145
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4