DNAJC2 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD217815A
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue  using DNAJC2 Polyclonal Antibody at dilution of 1:40(×200)
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using DNAJC2 Polyclonal Antibody at dilution of 1:40(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue  using DNAJC2 Polyclonal Antibody at dilution of 1:40(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using DNAJC2 Polyclonal Antibody at dilution of 1:40(×200)
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Overview

Circle
Product Name
DNAJC2 Polyclonal Antibody
Catalog Number
RD217815A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.

Immunogen Information

Circle
Immunogen
Synthetic peptide of human DNAJC2
Swissprot
Q99543
Synonyms
AU020218DnaJ (Hsp40) homolog subfamily C member 2DnaJ homolog subfamily C member 2Dnajc2DNJC2M phase phosphoprotein 11M-phase phosphoprotein 11MGC105894MIDA1MPHOSPH11MPP11OTTMUSP00000031226ZRF1Zrf2ZUO1Zuotin related factor 1Zuotin related
Gene Accession
NP055192

Applications

Circle
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
1.2 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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