DNMT3A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD86828A
Western blot analysis of extracts of various cell lines using DNMT3A Polyclonal Antibody
Immunofluorescence analysis of A549 cells using DNMT3A Polyclonal Antibody
Product Name
DNMT3A Polyclonal Antibody
Catalog Number
RD86828A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Immunogen Information
Immunogen
Recombinant protein of human DNMT3A
Gene ID
1788
Swissprot
Q9Y6K1
Synonyms
DNMT3ADNMT3A2M.HsaIIIATBRSDNMT3A
Calculated MW
106kDa/119kDa/121kDa/122kDa/124kDa/126kDa
Observed MW
125KDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000,IF 1:50-1:20
Concentration
1 mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas