DNMT3A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75502A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DNMT3A Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DNMT3A Polyclonal Antibody at dilution 1:50
Product Name
DNMT3A Polyclonal Antibody
Catalog Number
RD75502A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen Information
Immunogen
Recombinant protein of human DNMT3A
Swissprot
Q9Y6K1
Synonyms
DNA (cytosine 5) methyltransferase 3 alphaDNA (cytosine 5) methyltransferase 3ADNA (cytosine-5)-methyltransferase 3ADNA cytosine methyltransferase 3A2DNA methyltransferase 3 alphaDNA methyltransferase 3aDNA methyltransferase HsaIIIADNA MTase HsaIII
Gene Accession
BC043617
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas