DOK1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75149A
Western Blot analysis of Human hepatocellular carcinoma tissue and Jurkat cell using DOK1 Polyclonal Antibody at dilution of 1:450
Product Name
DOK1 Polyclonal Antibody
Catalog Number
RD75149A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Immunogen Information
Immunogen
Recombinant protein of human DOK1
Swissprot
Q99704
Synonyms
Docking protein 1 62kDDocking protein 1DOK 1DOK1DOK1Downstream of tyrosine kinase 1p62(dok)P62DOKpp62
Calculated MW
52 kDa
Gene Accession
BC114440
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas