The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.
Immunogen Information
Immunogen
A synthetic peptide of human Dot1L/KMT4
Gene ID
84444
Swissprot
Q8TEK3
Synonyms
DOT1LDOT1KMT4
Calculated MW
58kDa/61kDa
Observed MW
62kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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