DRAK2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77847A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DRAK2 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DRAK2 Polyclonal Antibody at dilution 1:40
Product Name
DRAK2 Polyclonal Antibody
Catalog Number
RD77847A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The full-lengthSTK17BcDNA clone encodes a deduced 372-amino acid protein with a molecular mass of 42.34 kD. The putative kinase domain is located at the N terminus and contains all 11 subdomains conserved among ser/thr kinases. STK17A andSTK17Bshare 59.7% amino acid identity.Northern blot analysis revealed that STK17B was expressed in various tissues, such as heart, placenta, liver, and pancreas, as different-sized transcripts, presumably due to differences in the 3-prime untranslated region. Transient transfection of COS-7 cells showed that STK17B localized in nuclei. Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis.
Immunogen Information
Immunogen
Recombinant protein of human STK17B
Swissprot
O94768
Synonyms
DAP kinase related apoptosis inducing proteinDAP kinase related apoptosis inducing protein kinase 2DAP kinase-related apoptosis-inducing protein kinase 2Death associated protein kinase related 2DRAK 2DRAK2Serine/threonine kinase 17bSerine/threonine
Gene Accession
BC016040
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas