DSCR1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78859A
Western Blot analysis of Mouse heart and brain tissue using DSCR1 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human liver cancer using DSCR1 Polyclonal Antibody at dilution of 1:45
Immunohistochemistry of paraffin-embedded Human brain using DSCR1 Polyclonal Antibody at dilution of 1:45
Product Name
DSCR1 Polyclonal Antibody
Catalog Number
RD78859A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human RCAN1
Swissprot
P53805
Synonyms
Adapt 78Adapt78Calcipressin 1Calcipressin-1Calcium and oxidant inducible mRNACSP 1CSP1Down syndrome candidate region 1Down syndrome critical region gene 1Down syndrome critical region protein 1DSC 1DSC1DSCR 1DSCR1MCIP 1MCIP1Modulatory calc
Calculated MW
28 kDa
Gene Accession
NP_004405
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas