Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.
Immunogen Information
Immunogen
Recombinant protein of human DSG2
Swissprot
Q14126
Synonyms
ARVC 10ARVC10ARVD 10ARVD10Cadherin family member 5CDHF 5CDHF5CMD1BBDesmoglein 2Desmoglein-2Desmoglein2DSG 2DSG2DSG2HDGCHDGC includedHuman Desmoglein colonMGC117034MGC117036MGC117037
Gene Accession
BC099655
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
1.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4