DUSP22 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD77405A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DUSP22 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DUSP22 Polyclonal Antibody at dilution 1:60
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Overview

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Product Name
DUSP22 Polyclonal Antibody
Catalog Number
RD77405A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.

Immunogen Information

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Immunogen
Recombinant protein of human DUSP22
Swissprot
Q9NRW4
Synonyms
Dual specificity protein phosphatase 22DUS22Dusp22JNK stimulatory phosphatase 1JNK-stimulatory phosphatase-1JSP 1JSP-1JSP1LMW DSP2LMW-DSP2Low molecular weight dual specificity phosphatase 2MAP kinase phosphatase xMitogen activated protein kina
Gene Accession
BC016844

Applications

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Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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