DUSP22 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD77405A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DUSP22 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DUSP22 Polyclonal Antibody at dilution 1:60
Variation
Quantity
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Overview
Circle
Product Name
DUSP22 Polyclonal Antibody
Catalog Number
RD77405A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Circle
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.
Immunogen Information
Circle
Immunogen
Recombinant protein of human DUSP22
Swissprot
Q9NRW4
Synonyms
Dual specificity protein phosphatase 22DUS22Dusp22JNK stimulatory phosphatase 1JNK-stimulatory phosphatase-1JSP 1JSP-1JSP1LMW DSP2LMW-DSP2Low molecular weight dual specificity phosphatase 2MAP kinase phosphatase xMitogen activated protein kina
Gene Accession
BC016844
Applications
Circle
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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