ECE2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77393A
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ECE2 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ECE2 Polyclonal Antibody at dilution 1:40
Product Name
ECE2 Polyclonal Antibody
Catalog Number
RD77393A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family. It converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.
Immunogen Information
Immunogen
Recombinant protein of human ECE2
Swissprot
O60344
Synonyms
ECE 2ECE-2ECE2ECE2Endothelin converting enzyme 2Endothelin-converting enzyme 2 regionHypothetical protein MGC2408KIAA0604MGC17664MGC78487
Gene Accession
BC005835
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas