ECE2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD79422A
Immunohistochemistry of paraffin-embedded Human ovarian cancer using ECE2 Polyclonal Antibody at dilution of 1/25
Western Blot analysis of A172 cells and Mouse liver tissue using ECE2 Polyclonal Antibody at dilution of 1/350
Variation
Quantity
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Overview
Product Name
ECE2 Polyclonal Antibody
Catalog Number
RD79422A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Fusion protein of human ECE2
Swissprot
O60344
Synonyms
ECE 2ECE-2ECE2ECE2Endothelin converting enzyme 2Endothelin-converting enzyme 2 regionHypothetical protein MGC2408KIAA0604MGC17664MGC78487
Calculated MW
100 kDa
Gene Accession
BC005835
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-2000, IHC 1:30-150, ELISA 1:2000-5000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas