Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity).
Immunogen Information
Immunogen
Fusion protein of human ECSIT
Swissprot
Q9BQ95
Synonyms
EcsitECSIT homologECSIT proteinECSITEvolutionarily conserved signaling intermediate in Toll pathwaymitochondrialEvolutionarily conserved signaling intermediate in Toll pathwaysLikely ortholog of mouse signaling intermediate in Toll pathway evoluti