EDARADD Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD88411A
Western blot analysis of extracts of mouse pancreas using EDARADD Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of mouse pancreas using EDARADD Polyclonal Antibody at 1:1000 dilution.
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Overview

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Product Name
EDARADD Polyclonal Antibody
Catalog Number
RD88411A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Immunogen Information

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Immunogen
Recombinant fusion protein of human EDARADD
Gene ID
128178
Swissprot
Q8WWZ3
Synonyms
EDARADDECTD11AECTD11BED3EDA3
Calculated MW
20kDa/31kDa
Observed MW
32kDa

Applications

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Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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