EIF3H Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78044A
Western Blot analysis of Human adrenal pheochromocytoma and fetal brain tissue using EIF3H Polyclonal Antibody at dilution of 1:1150
Immunohistochemistry of paraffin-embedded Human colon cancer using EIF3H Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human brain using EIF3H Polyclonal Antibody at dilution of 1:50
Product Name
EIF3H Polyclonal Antibody
Catalog Number
RD78044A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Immunogen Information
Immunogen
Recombinant protein of human EIF3H
Swissprot
O15372
Synonyms
eIF-3-gammaeIF3 gammaeIF3 p40eIF3 p40 subuniteIF3hEIF3HEIF3S3Eukaryotic translation initiation factor 3 subunit 3Eukaryotic translation initiation factor 3 subunit HMGC102958
Calculated MW
40 kDa
Gene Accession
BC000386
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas