This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection.
Immunogen Information
Immunogen
Recombinant protein of human EIF4EBP2
Swissprot
Q13542
Synonyms
4E-BP24EBP24EBP2eIF4E binding protein 2eIF4E-binding protein 2Eif4ebp2Eukaryotic translation initiation factor 4E binding protein 1Eukaryotic translation initiation factor 4E-binding protein 2PHASIIphosphorylatedheat and acid stable regulated by
Gene Accession
BC005057
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4