EIF4G3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87954A
Western blot analysis of extracts of various cell lines using EIF4G3 Polyclonal Antibody at 1:1000 dilution.
Product Name
EIF4G3 Polyclonal Antibody
Catalog Number
RD87954A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p.
Immunogen Information
Immunogen
Recombinant fusion protein of human EIF4G3
Gene ID
8672
Swissprot
O43432
Synonyms
EIF4G3eIF-4G 3eIF4G 3eIF4GIIeIF-4G3eIF4G3
Calculated MW
41kDa/43kDa/46kDa/47kDa
Observed MW
46kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.