The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
Immunogen Information
Immunogen
Recombinant protein of human ELAVL1
Swissprot
Q15717
Synonyms
ELAV (embryonic lethal abnormal vision Drosophila) like 1ELAV (embryonic lethalabnormal visionDrosophila) like 1 (Hu antigen R)ELAV like 1ELAV like RNA binding protein 1ELAV-like protein 1ELAV1ELAV1Elavl1Embryonic lethal abnormal vision drosophi
Calculated MW
36 kDa
Gene Accession
BC003376
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4